My Chemical Romance has been described as punk, rock, pop punk, post-hardcore, art rock, and more. The band has also been described as emo, emo punk, and emo pop, but Gerard Way, lead singer of the band, has categorically denied the label of “emo,” saying in a 2007 interview with the Maine Campus:

Basically, it’s never been accurate to describe us. Emo bands were being booked while we were touring with Christian metal bands because no one would book us on tours. I think emo is F–ing garbage, it’s bulls–. I think there’s bands that unfortunately we get lumped in with that are considered emo and by default that starts to make us emo. All I can say is anyone actually listening to the records, put the records next to each other and listen to them and there’s actually no similarities. I think emo’s a pile of s–.

In the immediate wake of the 2001 September 11 attacks, singer Gerard Way started the band My Chemical Romance with the goal of "making a difference." The song “Skylines and Turnstyles” was written about the 9/11 attacks and is featured on the band’s first studio album I Brought You My Bullets, You Brought Me Your Love, released on July 23, 2002.

My Chemical Romance was formed by Gerard Way in Newark, New Jersey.

My Chemical Romance gets its name from Ecstasy: Three Tales of Chemical Romance, a book by Irvine Welsh. Mikey Way, the band’s bassist, suggested the name after seeing the book while working at a bookstore.

The original members of My Chemical Romance included:

• Gerard Way on lead vocals
• Mikey Way on bass
• Matt Pelissier on drums and percussion
• Ray Toro on lead guitar and backing vocals
• Frank Iero on rythym guitar and backing vocals

Pelsier left in 2004 and was replaced by Bob Bryar who remained the band’s drummer and percussionist until 2010 when he was replaced by Jarrod Alexander who remained with the band until it broke up in 2013. When the band reunited, Gerard and Mikey Way, Ray Toro, and Frank Iero returned with Jarrod Alexander as a touring member.

When the band embarked on The Black Parade World Tour in February 2007, Bob Bryar started experiencing wrist issues that caused him to be unable to perform with the band. Due to his injuries, he would officially depart from My Chemical Romance on March 3, 2010.

The Black Parade was released on October 20, 2006. It was the third studio album released by My Chemical Romance.

The My Chemical Romance fanbase is referred to as "Killjoys." The band's fourth studio album Danger Days: The True Lives of the Fabulous Killjoys is said to be the inspiration for the name.

On March 22, 2013, My Chemical Romance confirmed that it had broken up. Despite the band’s dissolution, My Chemical Romance released two albums before reuniting in 2017:

1. On March 25, 2014, the band released the greatest hits compilation album May Death Never Stop You
2. On September 23, 2016, the band released The Black Parade/Living with Ghosts, a 10 year anniversary re-release of The Black Parade.

My Chemical Romance officially announced its reunion on December 20, 2019. However, it was later revealed the band had actually reunited in 2017, more than 2 years prior to the official announcement.

My Chemical Romance has had 1,048 concerts.

My Chemical Romance is most often considered to be Rock, Punk, Alternative Rock, Alternative, Hard Rock, Punk Rock, Pop Punk, Emo, Post-Hardcore, Modern Rock, and Pov: Indie.

The next My Chemical Romance concert is on October 19, 2024 at Las Vegas Festival Grounds in Las Vegas, Nevada, United States. The bands performing are: My Chemical Romance / Fall Out Boy / A Day To Remember / Dashboard Confessional / Simple Plan / Coheed and Cambria / Underoath / The Distillers / Mayday Parade / Chiodos / Movements / Bayside / The Maine / Saves The Day / The Wonder Years / The Starting Line / August Burns Red / Thursday / State Champs / Atreyu / Hawthorne Heights / Cartel / Tonight Alive / Saosin / We The Kings / Pretty Girls Make Graves / The Red Jumpsuit Apparatus / Alesana / L.S. Dunes / Daisy Grenade / We Are the In Crowd / Jimmy Eat World / Pierce the Veil / The Used / The All-American Rejects / New Found Glory / Dance Gavin Dance / Motion City Soundtrack / Silverstein / Basement / Sleeping With Sirens / Neck Deep / Cobra Starship / Story of the Year / Say Anything / Four Year Strong / Mom Jeans. / Senses Fail / 3OH!3 / Anberlin / Armor for Sleep / Hey Monday / The Devil Wears Prada / Escape the Fate / Nada Surf / Emery / Against the Current / Millionaires / The Forecast / CARR / Taking Back Sunday.

The last My Chemical Romance concert was on October 27, 2023 at Garden Amphitheatre in Garden Grove, California, United States. The bands that performed were: Rob Zombie / My Chemical Romance / Avenged Sevenfold / Deftones.

The songs that My Chemical Romance performs live vary, but here's the latest setlist that we have from the March 26, 2023 concert at INTEX Osaka in Osaka, Ōsaka, Japan:

1. The Foundations of Decay
2. Na Na Na (Na Na Na Na Na Na Na Na Na)
3. Thank You for the Venom
4. Boy Division
5. I'm Not Okay (I Promise)
6. The Ghost of You
7. Bury Me in Black
8. It's Not a Fashion Statement, It's a Fucking Deathwish
9. You Know What They Do to Guys Like Us in Prison
10. Welcome to the Black Parade
11. This Is How I Disappear
12. Everybody Hates the Eagles
13. The World Is Ugly
14. Give 'Em Hell, Kid
15. Teenagers
16. Mama
17. Helena
18. Famous Last Words
19. Sleep
20. Vampires Will Never Hurt You